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Week 1 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay returns 25-1

The New Orleans Saints supplied one of the crucial lopsided and shocking outcomes of Week 1 final season with a 38-3 win over the Green Bay Packers. The Packers will attempt to keep away from one other letdown to start out this 12 months after they tackle the division-rival Minnesota Vikings. New Minnesota head coach Kevin O’Connell and offensive coordinator Wes Phillips come to the Vikings contemporary off a Super Bowl win with the Los Angeles Rams, and the two-point line is among the narrowest within the Week 1 NFL odds on Caesars Sportsbook. The Saints are 5.5-point street favorites within the NFL traces of their matchup towards an Atlanta Falcons workforce reloaded with a bunch of younger expertise. Earlier than you make any Week 1 NFL picks or NFL parlays, you’ll want to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The mannequin, which simulates each NFL recreation 10,000 occasions, is up over $7,500 for $100 gamers on top-rated NFL picks since its inception. The mannequin enters the 2022 NFL season on an unbelievable 138-97 run on top-rated NFL picks that dates again to the 2017 season. Amazingly, it hasn’t missed a top-rated choose since Week 15 final season. 

The mannequin additionally ranked within the prime 10 on NFLPickWatch 4 of the previous six years on straight-up NFL picks and beat greater than 94 % of CBS Sports activities Soccer Decide’em gamers 4 occasions throughout that span. Anybody who has adopted it’s method up.

Now, the mannequin has locked in 5 assured NFL finest bets for Week 1. In case you efficiently parlay its picks, you would be taking a look at an enormous payout of round 25-1. You can only see the model’s Week 1 NFL picks at SportsLine

High Week 1 NFL picks

After simulating each recreation 10,000 occasions, the mannequin is excessive on the Indianapolis Colts to cowl as eight-point street favorites towards the Houston Texans. Quarterback play has held the Colts again since Andrew Luck shocked the NFL world in 2019. Indianapolis hopes it has discovered its finest answer but in veteran Matt Ryan, whom it acquired from the Falcons within the offseason. Ryan ought to get a comparatively gentle take a look at in his debut towards a Texans squad that ranked twenty seventh in scoring protection final 12 months.

The mannequin tasks an environment friendly 21-of-31 passing day for round 250 yards and two scores for Ryan. Working again Jonathan Taylor, in the meantime, simply clears 100 yards on the bottom. The Colts rating 29 factors and canopy in nearly 60% of simulations, making them a powerful alternative in your Week 1 NFL parlays. See which other NFL parlay picks to make here.

How one can make Week 1 NFL parlays

The mannequin additionally jumped on 4 different NFL matchups the place it says the road is method off, together with an underdog that wins outright. You can only see the model’s NFL Week 1 best bets and parlay at SportsLine

What are the mannequin’s prime Week 1 NFL picks? And which different NFL matchups do you have to goal for a powerful 25-1 payout? Visit SportsLine now to see the Week 1 NFL best bets from a model on a 138-97 run on its top-rated picks, and discover out.

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